Revealing the structure of fibrotic substrate in the ventricle

ADAS 3D LV enables better visualization of the LV fibrotic substrate for pre-procedural clinical decision making.

Case example

ADAS 3D LV offers the electrophysiologist information to better understand and plan the approach before and during the intervention.

Before the intervention

This case example (courtesy of Dr Antonio Berruezo, Hospital Clínic de Barcelona, Spain) shows the MRI data from a patient's Left Ventricle (LV). ADAS 3D LV was used to obtain the LV, RV and aorta, and to detect potential corridors in the LV. There are several corridors detected (blue area shows border-zone corridor).

During the intervention

The planning data, including the corridors and other relevant myocardial information, was exported from ADAS 3D LV to files in formats accepted by EP navigation system. These files were imported into the catheter navigation system and used as assistance to the electroanatomical mapping.

ADAS 3D LV data for the patient above serves as guide the perform the electroanatomical mapping. The left window shows the EAM data, and right window the ADAS 3D LV.

After the intervention

ADAS 3D LV can load data from the EP navigation system and be used to compare MRI information to electro-anatomical data (for research only).

Software Information

ADAS 3D LV is a standalone Windows-based post-processing software solution for cardiac Late Gadolinium-enhanced DICOM images.


  • DICOM Late Gadolinium Enhanced
  • Cardiac MRI data from various sources
  • 2D GRE and 3D NAV GRE
  • Automatic Alignment of 2D GRE slices
  • Inspection of DICOM attributes
  • Preview DICOM images without loading

3D viewer

  • Five cardiac anatomy views: 3D, 2D, 3D-sync-2D, Multi3D and Multi2D
  • 3D interactive visualization of the myocardium by means of transmural LAYERS
  • 3D-sync-2D: to understand MRI-to-3D Cardiac model correspondence
  • Multi3D: multi-window synchronized view to visualize multiple LAYERS to appreciate transmurality in one screen
  • Multi2D: multi-window view of short-axis
  • Selective 3D visualization of Left Ventricle, Right Ventricle, Aorta & scar Core

Study Storage Database

  • Storage and management of processed studies for later review
  • Search by patient name or ID, or Study name
  • Store multiple studies per patient
  • Exchange ADAS 3D LV studies between users

Tissue characterization

  • 3D Cardiac Model Segmentation including Left Ventricle, Right Ventricle and Aorta
  • Automatic classification of tissue using selectable imaging thresholds
  • Computation of LAYERS, scar Core, and Tissue Boundaries
  • EP-navigation friendly colour mappings to visualize tissue

Corridors detection

  • Automatic transmural detection of border-zone corridors for the left ventricle
  • Selective visualization of CORRIDORS
  • Display of CORRIDORS as either (a) centreline, (b) 3D volume or (c) volume intersecting with LAYERS
  • Quantitative analysis for each CORRIDOR (mass)


  • Help guide the procedure by exporting structures (including anatomy, fibrosis information and corridors) to formats compatible with EP navigation systems
  • Generation of video showing LAYER transmurality from endo to epicardium
  • Generation of snapshots in standard picture formats to keep a record and share the case


Visualize the inside of the myocardium in 3D

Identify corridors of borderzone tissue

Help decide the approach (Endo, Epi, Combined)

Export LV and other structures to formats accepted by navigation systems


ADAS 3D is developed in partnership with Hospital Clínic de Barcelona, Spain.

Hospital Clínic de Barcelona


ADAS 3D LV is being evaluated clinically in collaboration with:

Herzzentrum Leipzig, Germany. Prof Gerhard Hindricks, Director of the Department of Electrophysiology • Johns Hopkins Hospital, Baltimore, USA. Prof Henry Halperin, Co-Director, Johns Hopkins Imaging Institute of Excellence • Cardiocentro Ticino, Lugano, Switzerland. Prof Angelo Auricchio, Director of the Heart Failure Program and Clinical Electrophysiology Unit • Hospital of the University of Pennsylvania, Philadelphia, USA. Prof Francis Marchlinski, Director of Electrophysiology Laboratory. Prof Saman Nazarian. Prof Harold Litt, Chief, Cardiovascular Imaging Section, Radiology • INCOR, Sao Paulo, Brazil. Prof Mauricio Scanavacca, Diretor da Unidade Clinica de Arrritmia e Marcapasso • National University Hospital, Singapore. Dr Pipin Kojodjojo, Department of Cardiology • Guglielmo da Saliceto Hospital, Piacenza, Italy. Dr Diego Penela, Department of Cardiology • CEDIMED, Medellin, Colombia. Dr Alejandro Zuluaga, Radiology • St Antonius Ziekenhuis, Nieuwegein, The Netherlands. Prof Lucas Boersma, Head of Cardiology • Coburg Herzzentrum, Germany. Prof Sonia Busch, Leitende Oberärztin für Elektrophysiologie • Hospital Universitario Virgen del Rocio, Seville, Spain. Dr Juan Acosta,Department of Cardiology • Barts Heart Centre, London, UK. Prof Richard Schilling, Director Cardiovascular CAG

See also

ADAS 3D LV Product Better visualization of the LV fibrotic substrate.

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